Gene information
Official symbol GP1BA
Official full name glycoprotein Ib platelet subunit alpha
Gene type protein-coding gene
Chromosome17p13.2
Alias symbolCD42b; GPIbalpha
Previous symbolGP1B
Gene familyCD molecules
Resources
Entrez Gene 2811
HGNC HGNC:4439
Ensembl ENSG00000185245
Vega OTTHUMG00000177946
UCSC uc021tnz.1
GO terms: 29 records
GO Description Category LogP Number of genes Detail
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001653 peptide receptor activity GO Molecular Functions -6.43798881 12 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0006816 calcium ion transport GO Biological Processes -5.55009887 27 More
GO:0008528 G protein-coupled peptide receptor activity GO Molecular Functions -6.62401664 12 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0010543 regulation of platelet activation GO Biological Processes -12.2843439 12 More
GO:0030001 metal ion transport GO Biological Processes -7.54203733 26 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030099 myeloid cell differentiation GO Biological Processes -6.71806250 15 More
GO:0030219 megakaryocyte differentiation GO Biological Processes -3.12309097 6 More
GO:0031225 anchored component of membrane GO Cellular Components -4.51589396 20 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0042730 fibrinolysis GO Biological Processes -16.7830831 11 More
GO:0043235 receptor complex GO Cellular Components -19.4198369 40 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0051209 release of sequestered calcium ion into cytosol GO Biological Processes -4.43542328 10 More
GO:0051282 regulation of sequestering of calcium ion GO Biological Processes -7.93009971 22 More
GO:0051283 negative regulation of sequestering of calcium ion GO Biological Processes -4.35719226 10 More
GO:0060348 bone development GO Biological Processes -12.2474877 36 More
GO:0070588 calcium ion transmembrane transport GO Biological Processes -2.54626507 17 More
GO:0097553 calcium ion transmembrane import into cytosol GO Biological Processes -4.27502414 13 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0098609 cell-cell adhesion GO Biological Processes -15.7963965 69 More
GO:0098655 cation transmembrane transport GO Biological Processes -3.98966777 20 More
GO:0098660 inorganic ion transmembrane transport GO Biological Processes -4.47276690 21 More
GO:0098662 inorganic cation transmembrane transport GO Biological Processes -4.65654157 20 More
GO:0098797 plasma membrane protein complex GO Cellular Components -14.6387951 39 More
GO:0098802 plasma membrane signaling receptor complex GO Cellular Components -6.47096721 17 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04512 ECM-receptor interaction KEGG Pathway -16.8587083 28 More
hsa04611 Platelet activation KEGG Pathway -14.0379587 18 More
hsa04613 Neutrophil extracellular trap formation KEGG Pathway -12.8071279 20 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
aspirin PharmGKB 1724533118417193 view
Related studies: 5 records
Molecular factor Omics type Application Objective MI type Reference
NM_000173.7:c.[482C>T;-5T>C] genomics myocardial infarction[diagnosis] myocardial infarction Pellikka M et al. J Thromb Thrombolysis. 2008
GP1BA VNTR genomics myocardial infarction[diagnosis] myocardial infarction Ozelo MC et al. Thromb Haemost. 2004
GP1BA VNTR genomics acute myocardial infarction[diagnosis] acute myocardial infarction Dogra RK et al. J Thromb Thrombolysis. 2012
NM_000173.7:c.482C>T genomics myocardial infarction[diagnosis] myocardial infarction Pina-Cabral LB et al. Rev Port Cardiol. 2018
NM_000173.7:c.482C>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Mikkelsson J et al. Circulation. 2001
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